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Volume 2, published in 1847, consists of letters of Christopher Columbus to the Treasurer of the King and Queen of Washington Irving (April 3, 1783 - November 28, 1859) was an American author of the early 19th century.

Best known for his short stories The Legend of Sleepy Hollow and Rip van Winkle (both of which appear in his book The Sketch Book of Geoffrey Crayon), he was also a prolific essayist, biographer and historian.

Nerves are large enough to have been recognized by the ancient Egyptians, Greeks, and Romans, but their internal structure was not understood until it became possible to examine them using a microscope.

"It is difficult to believe that until approximately year 1900 it was not known that neurons are the basic units of the brain (Santiago Ram? Equally surprising is the fact that the concept of chemical transmission in the brain was not known until around 1930 (Henry Hallett Dale) and (Otto Loewi).

The PNS is divided into a) somatic and b) autonomic nervous system, and c) the enteric nervous system. The autonomic nervous system is further subdivided into the sympathetic and the parasympathetic nervous systems.

The sympathetic nervous system is activated in cases of emergencies to mobilize energy, while the parasympathetic nervous system is activated when organisms are in a relaxed state.

Nerves that transmit signals from the brain are called motor or efferent nerves, while those nerves that transmit information from the body to the CNS are called sensory or afferent.

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There is an anatomical convention that a cluster of neurons in the brain or spinal cord is called a nucleus, whereas a cluster of neurons in the periphery is called a ganglion.

Irving and James Fenimore Cooper were the first American writers to earn acclaim in Europe, and Irving is said to have encouraged authors such as Nathaniel Hawthorne, Henry Wadsworth Longfellow, and Edgar Allan Poe.

The nervous system is the part of an animal's body that coordinates its actions and transmits signals to and from different parts of its body.

The enteric nervous system functions to control the gastrointestinal system.

Both autonomic and enteric nervous systems function involuntarily.

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